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Association of variantion of a gene responsible for transporting uric acid with early onset pre-eclampsia in Indian population

Association of single nucleotide polymorphism of uric acid transporter gene, SLC2A9 rs1014290, with early onset pre-eclampsia in Indian population - NIL

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/06/068602
Enrollment
100
Registered
2024-06-07
Start date
Unknown
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O141- Severe pre-eclampsia

Interventions

Intervention1: Nil: Nil Control Intervention1: Nil: Nil

Sponsors

Maulana Azad Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Female patients of age greater than 18yrs attending Obstetrics and Gynaecology ANC clinic or admitted in IPD of LNJP Hospital with diagnosis of preeclampsia before gestational age of 34 weeks and consents to participate in the study. Controls: Age matched healthy pregnant women who have stayed normotensive till the gestational age of 34 weeks with no prior history of hypertension, hyperuricemia, gout

Exclusion criteria

Exclusion criteria: Known case of chronic hypertension, diabetes mellitus, Anti-Phospholipid Antibody Syndrome(APLA), Chronic Kidney Disease(CKD), vasculitis, gout, cancer.

Design outcomes

Primary

MeasureTime frame
Association of SNP rs1014290 of uric acid transporter gene SLC2A9 with early onset pre-eclampsia.Timepoint: 1 year—

Secondary

MeasureTime frame
Association of SLC2A9 rs1014290 with uric acid levels and NLRP3 inflammasome mediated immune response in patients with early onset pre-eclampsia.Timepoint: 1 year—

Countries

India

Contacts

Public ContactDr Johncy George

Maulana Azad Medical College

debnathekta@yahoo.in9013583844

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026