Comparative study to find the effective dose of sugammadex to reverse the eefectbof muscle relaxants in patients undergoing General Surgery receiving muscle relaxants in general anesthesia

Comparative Study for the Efficacy of Sugammadex 1mg/kg and 2mg/kg for the Reversal of Neuromuscular blockade after Vecuronium for patients undergoing Elective surgery Under General Anaesthesia - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/06/068590

Enrollment

Registered

2024-06-07

Start date

Unknown

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Sugamadex: Sugamadex 1mg/kg will given at TOF Count 2 in one group till TOF count reaches 0.9, and sugamadex 2mg/kg will be given at TOF count of 2 in another group till TOF count reach

Eligibility

Inclusion criteria

Inclusion criteria: Patients included under ASA grade 1 and 2

Exclusion criteria

Exclusion criteria: 1. Renal dysfunction 2. Allergic to muscle relaxants 3. Pregnant females, breastfeeding females 4. History of chronic obstructive pulmonary disease

Design outcomes

Primary

Measure	Time frame
1. The response to train - of - four stimulation just before sugammadex administrationTimepoint: Muscle power,level of consciousness after extubation for 2minutes, 5minutes,10minutes,30minutes ,60minutes	—

Secondary

Measure	Time frame
The incidence of recurrent paralysis during the postoperative monitoring periodTimepoint: 15minutes, 30minutes,1hour after reversal	—

Countries

India

Contacts

Public ContactDr Srinivasalu

VIJAYANAGAR INSTITUTE OF MEDICAL SCIENCES BALLARI

goudarkavya@gmail.com8618545060

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026