Health Condition 1: L208- Other atopic dermatitis
Conditions
Interventions
Intervention1: Probiotic formulation: Each 1 gram sachet (given once daily) contains:
â?¢ Probiotic Blend - 5 Billion CFU containing
Lactobacillus johnsonii UBLJ-01-3.8 billion cfu
Sponsors
Unique Biotech Ltd.
Eligibility
Inclusion criteria
Inclusion criteria: 1) Patients with age of two to eighteen years diagnosed with atopic dermatitis (mild to moderate (SCORAD of 50).
Exclusion criteria
Exclusion criteria: 1) Patient with associated (inflammatory and infectious) skin diseases 2) Patients using oral corticosteroids or monoclonal antibodies or immunosuppressants within 30 days before enrolment. 3) Use of phototherapy for AD in the previous 2 months. 4) Probiotic intake in the previous 2 months. 5) Systemic antibiotic treatment in the previous 4 days; fever 6) Patients in whom any of the study products is contraindicated. 7) Patients who have participated in research studies with medicinal products during the previous 3 months. 8) patients with gluten or lactose intolerance or inflammatory bowel disease (Crohn disease or ulcerative colitis)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A clinical tool used to assess the extent and severity of disease i.e. SCORAD (SCORing Atopic Dermatitis) Index of 0 after six monthsTimepoint: 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum cytokines such as IL17 ( 17a, 17c), IL-4, IL-6,IL-10, IL-13, IFN-gamma & TNF-alpha (Reduced serum concentration of inflammatory cytokines) Serum IgE levels & Absolute eosinophil count (AEC) will be assessed.Timepoint: 6 months | — |
Countries
India
Contacts
Public ContactDr Manoj Kumar Tembhre
All India Institute of Medical Sciences (AIIMS), New Delhi
Outcome results
None listed