Effectiveness of Ozonated oil in reducing the severity of chronic periodontitis after scaling and root planing as an alternative to chlorhexidine

Effectiveness of ozonated oil versus chlorhexidine gel in patients with chronic periodontitis- A randomized control trial - Nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/06/068548

Enrollment

Registered

2024-06-06

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis Health Condition 2: A498- Other bacterial infections of unspecified site

Interventions

Intervention1: Ozonated oil: Ozonated oil To be used topically for oral application for 30 days, once in a day Control Intervention1: Chlorhexidine gel: Chlorhexidine gel to be used topically for oral

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients suffering from chronic periodontitis with a minimum of at least 10 teeth present in each arch. 2. Bleeding on probing 3. Pocket depth of at least 3 mm 4. Loss of attachment more than 2 mm

Exclusion criteria

Exclusion criteria: 1. Patient with history of any systemic disease such as diabetes, hypertension, anaemia and systemic disease related to periodontitis. 2. Patients with fixed prosthesis, removable prosthesis or any orthodontic appliance. 3. Pregnancy or breastfeeding. 4. Use of systemic drugs in last 3 months. 5. Patients who have undergone scaling and root planing in the last 6 month

Design outcomes

Primary

Measure	Time frame
effectiveness of ozonated oil over chlorhexidine gel in the treatment of chronic periodontitisTimepoint: Baseline, 1 month and 3 months	—

Secondary

Measure	Time frame
Reduction of clinical attachment level after scaling and root planing and topical application of ozone oilTimepoint: Baseline, 1 month and 3 months;Reduction of gingival score after scaling and root planing and topical application of ozone oilTimepoint: Baseline, 1 month and 3 months;Reduction of periodontal probing depth after scaling and root planing and topical application of ozone oilTimepoint: Baseline, 1 month and 3 months;Reduction of plaque score after scaling and root planing and topical application of ozone oilTimepoint: Baseline, 1 month and 3 months	—

Measure

Time frame

Reduction of clinical attachment level after scaling and root planing and topical application of ozone oilTimepoint: Baseline, 1 month and 3 months;Reduction of gingival score after scaling and root planing and topical application of ozone oilTimepoint: Baseline, 1 month and 3 months;Reduction of periodontal probing depth after scaling and root planing and topical application of ozone oilTimepoint: Baseline, 1 month and 3 months;Reduction of plaque score after scaling and root planing and topical application of ozone oilTimepoint: Baseline, 1 month and 3 months

—

Countries

India

Contacts

Public ContactAvishek Singh

NIMS Dental College and Hospital, Jaipur

naganandini36@gmail.com9622338053

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026