A Clinical trail on Parangipattai chooranam in the management of Azhal keel vaayu (Osteoarthritis of Knee) among patients attending OPD and IPD of Government Siddha Medical College and Hospital, Palayamkottai

A Prospective,open labelled, single arm,non randomized, single centric,phase II,clinical trial to determine the effectiveness of parangipattai chooranam in the management of azhal keel vaayu (osteoarthritis of knee) - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/06/068546

Enrollment

Registered

2024-06-06

Start date

Unknown

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M170- Bilateral primary osteoarthritis of knee

Interventions

Intervention1: PARANGIPATTAI CHOORANAM: DOSAGE:1 to 3 gms,twice a day orally for 48 days with milk Control Intervention1: NIL: NIL

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients presenting with Joint pain 2.Morning stiffness for less than 30 minutes 3.Crepitus on active movements 4.Joint line tenderness 5.Difficulty in Range of motion 6.Patient presenting with or without swelling

Exclusion criteria

Exclusion criteria: 1. Patients with history of Trauma and post- trauma 2.Ligament tear 3.Patient undergone knee replacement surgery 4.Metabolic joint disease 5.Infectious joint disease(tuberculosis,polyarthritis) 6.Inflammatory arthritis(Rheumatoid arthritis) 7.Septic arthritis 8.Osteomyelitis 9.Chronic liver and renal diseases. 10.Malignancy

Design outcomes

Primary

Measure	Time frame
The outcome will be aimed at reducing the symptoms of Azhal keel vaayu and to determine the effectiveness of parangipattai chooranamTimepoint: 48 days	—

Secondary

Measure	Time frame
1.To collect various aspects of Azhal keel vaayu in Siddha literatures. 2.To evaluate physico chemical,phyto chemical and bio chemical characters of parangipattai chooranam. 3. To evaluate safety profile for assessing acute and sub-acute toxicity of trial drug parangipattai chooranam. 4.To evaluate pharmacological analysis of parangipattaichooranam. 5.Study about the prevalence of Azhal keel vaayu in relation between diet and life style. 6.To evaluate siddha parameters (including Envagai thervu) changes and dhegi in Azhal keel vaayu during the study period. 7. To evaluate modern parametric changes in Azhal keel vaayu. 8.To document the Bio statistical analysis. 9. To assess the Quality of life of azhal keel vaayu patients.Timepoint: 6 months	—

Measure

Time frame

1.To collect various aspects of Azhal keel vaayu in Siddha literatures. 2.To evaluate physico chemical,phyto chemical and bio chemical characters of parangipattai chooranam. 3. To evaluate safety profile for assessing acute and sub-acute toxicity of trial drug parangipattai chooranam. 4.To evaluate pharmacological analysis of parangipattaichooranam. 5.Study about the prevalence of Azhal keel vaayu in relation between diet and life style. 6.To evaluate siddha parameters (including Envagai thervu) changes and dhegi in Azhal keel vaayu during the study period. 7. To evaluate modern parametric changes in Azhal keel vaayu. 8.To document the Bio statistical analysis. 9. To assess the Quality of life of azhal keel vaayu patients.Timepoint: 6 months

—

Countries

India

Contacts

Public ContactProf Dr T Komalavalli Alias Mehala

Government Siddha Medical College and Hospital

drpsk_md@yahoo.in9944337757

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026