Health Condition 1: PCS- Health Condition 2: K958- Complications of other bariatric procedure Health Condition 3: K87- Disorders of gallbladder, biliarytract and pancreas in diseases classified elsewhere Health Condition 4: K918- Other intraoperative and postprocedural complications and disorders of digestive system Health Condition 5: N998- Other intraoperative and postprocedural complications and disorders of genitourinary system
Conditions
Interventions
Intervention1: The study group (HPI guided group): • Hemodynamic management will be based on the hemodynamic parameters provided by the HemoSphere platform with the Acumen IQ sensor, including CI, SVV
Sponsors
Self
Eligibility
Inclusion criteria
Inclusion criteria: 1) Age of subject 18 years and above 2) Scheduled for elective major abdominal surgery. 3) ASA grade II – IV 4) Need for continuous invasive blood pressure monitoring.
Exclusion criteria
Exclusion criteria: 1)Patients with significant hypotension as measured before surgery. 2) patients with known left or right cardiac failure, known arrythmias (e.g., atrial fibrillation), cardiac shunts, severe aortic stenosis or the need for dialysis will be excluded. 3) If surgery included clamping of the aorta or Pringle’s manoeuvre, the patient is not eligible for the trial. 4) Finally, emergency procedures will also be excluded from the trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| determination of time weighted average(TWA) spent by the study group and control group in the trialTimepoint: Time weighted average will be calculated soon after the end of Anaesthesia for the specific surgery. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Determination of the incidence of intraoperative hypotension, i.e. the number of hypotensive events, total time (in minutes) spent with hypotension & the percentage of time spent in hypotension during surgery. 2) Determining the effect of hypotensive episodes & its duration & its effect on postoperative mortality (28 days) in form of myocardial ischemia, & acute kidney injury (AKI) as well as prolonged stay in ICU Timepoint: 1)KDIGO classification of AKI as SCr0.3 mg/dl from baseline within 48 hours, 1.5 times the baseline SCr within 7 days, or urine output less than 0.5 ml/kg/hr for more than 6 hours of urine output will be used to assess intraop and postop AKI occurrence. 2) ECG will be done pre op, post op at 24 hrs & 48 hrs respectively to detect any early changes of myocardial ischemia. 3) Pt/primary relative will be contacted telephonically to confirm about morbidity/mortality at 28 days postop. | — |
Countries
India
Contacts
Public ContactDr Premlal Sreekumar
Outcome results
None listed