Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Total Intravenous Anaesthesia: The patient will be shifted to the operation theatre and standard ASA monitors will be attached, along with BIS. Patients will be pre-medicated for genera
Sponsors
Maulana Azad Medical College and associated Lok Nayak Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1. ASA II or III 2. Well controlled type 2 diabetic patients using oral hypoglycaemic agents or insulin. 3. Elective open abdominal surgery. 4. Duration of surgery 2 to 6 hours.
Exclusion criteria
Exclusion criteria: 1. Diabetic ketoacidosis or diabetic neuropathy. 2. Hepatic and/or renal dysfunction. 3. Pancreatic cancer or islet cell tumours. 4. Patients receiving drugs with known effects on sympathetic response or hormonal secretion such as beta blockers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum cortisol to DHEAS ratio before and after the surgery and comparing the values between the total intravenous anaesthesia and inhalational anaesthesia groups in T2DM patients.Timepoint: 30 minutes before surgery 24 hours after completion of surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Percentage of post operative complications and outcomes in TIVA and inhalational anaesthetic techniques in diabetic patients undergoing abdominal surgery using EPCO definitions at 24 hours after surgery.Timepoint: 24 hours after completion of surgery;Serum glucose, insulin and C-peptide in diabetic patients receiving intravenous or inhalational anaesthesia at different points of time.Timepoint: 30 minutes before surgery 24 hours after completion of surgery | — |
Countries
India
Contacts
Public ContactDr Shivika Malik
Maulana Azad Medical College
Outcome results
None listed