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We are comparing the effect of Erector Spinae plane block versus Peritumoral Local Anaesthetic infiltration on Post operative immune response in patients undergoing surgery for Modified radical mastectomy

Effect of Erector Spinae plane block versus Peritumoral Local Anaesthetic infiltration on Post operative immune response in patients undergoing surgery for breast cancer - NIL

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/06/068501
Enrollment
34
Registered
2024-06-06
Start date
Unknown
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Erector Spinae block: After induction of general anaesthesia ultrasound guided single shot Erector spinae block at T4 vertebral level will be performed using in-plane technique and 20 m

Sponsors

Maulana Azad Medical College & associated Lok Nayak Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)Age18-65 years 2)ASA physical status I,II&III 3)unilateral breast cancer

Exclusion criteria

Exclusion criteria: 1. BMI more than 35kg/m2 2. any structural deformity of thoracic spine 3. known allergy to LA drugs 4. any infection at the site of block or infiltration

Design outcomes

Primary

MeasureTime frame
1)Neutrophil to lymphocyte ratio in both the groups 2)Platelet to lymphocyte ratio in both the groups.Timepoint: baseline and 24 hours after surgery

Secondary

MeasureTime frame
Mean difference in serum 1interleukin (IL)-6,IL-8 and vascular endothelial growth factor (VEGF) levels in both the groups at 24 hrs after surgery Timepoint: 24 hours after surgery;Quality of recovery-15Timepoint: 24 hours after surgery;Time to return to intended oncological therapyTimepoint: 3 weeks or 4 weeks after surgery;Total consumption of opioidsTimepoint: 24 hours after surgery

Countries

India

Contacts

Public ContactPathan Arief

Maulana Azad Medical College

arief16051997@gmail.com9968527122

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026