Role of Negative pressure wound therapy in prevention of Surgical site infection in grossly contaminated emergency abdominal surgeries

A Randomized Controlled Trial to compare the outcome of Negative pressure wound therapy in primary versus delayed primary skin closure in CDC Class IV laparotomy wounds - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/06/068497

Enrollment

Registered

2024-06-06

Start date

Unknown

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Negative pressure wound dressing over primary closed abdominal skin wound: Negative pressure wound dressing over primary closed abdominal surgery wound on Post operative day 1 and remov

Eligibility

Inclusion criteria

Inclusion criteria: 1.All emergency midline laparotomy with CDC class IV wounds 2.Age 18-75 years 3.Ready to give consent for participation in the study

Exclusion criteria

Exclusion criteria: 1.Immunocompromised patients 2.ICU patient requiring ventilator support 3.Non Hollow viscous perforation peritonitis.

Design outcomes

Primary

Measure	Time frame
To compare the rate of SSI in Emergency laparotomy Class IV wounds with or without NPWTTimepoint: 60 days or day of mortality	—

Secondary

Measure	Time frame
To assess the post operative hospital stay, time to skin closure, Quality of Life assessment by SF 36 questionnaire and Assessment of wound healing progress by Redness, Oedema, Ecchymosis, Discharge and Approximation (REEDA) scale and Vancouver Scar Scale (VSS) in Emergency laparotomy Class IV wounds with or without NPWTTimepoint: 60 days or day of mortality	—

Countries

India

Contacts

Public ContactDr Ujjwal Singh Shikhar

Institute of medical sciences, Banaras Hindu University

vivekims97@gmail.com9453792147

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026