Health Condition 1: K089- Disorder of teeth and supporting structures, unspecified Health Condition 2: K088- Other specified disorders of teethand supporting structures
Conditions
Interventions
Intervention1: oral nutraceutical supplement: ( collagen + sodium hyaluronate + curcumin + Boswellia + Piperine )
Control Intervention1: PLACEBO GROUP: PLACEBO GROUP ( TAB PLACEBO BD x 2 months )
Sponsors
Vaibhav Alone
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients who have given written informed consent to be a part of the study. 2. Adult patients of either sex Age 18-60 years 3. ASA I or ll 4.Patients with Wilkes classification of Internal Derangement stage III and stage IV only with positive Mahan test
Exclusion criteria
Exclusion criteria: 1. Age <18 years and >60 years 2. Pregnant or lactating female 3. Patients with severe debilitating conditions such as uncontrolled diabetes mellitus, uncontrolled hypertension, cardio respiratory conditions, previous history of cerebrovascular accidents, myocardial infarction, coronary artery disease, impaired renal and hepatic function and coagulation disorders 4.Patients on antiplatelet/anticoagulant therapy. 5.autoimmune diseases affecting joints 6.Significant mechanical obstruction that prevents mouth opening, 7.Acute capsulitis , synovitis 8.Benign or malignant temporomandibular joint lesions, 9.Neurological disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate and compare the analgesic efficacy oral nutraceutical (Collagen + sodium hyaluronate + Curcurmin + Boswellia + piperine) as adjunct to arthrocentesis- iPRF in management of patients with Temporomandibular joint derangement .Timepoint: DAY 0 7 DAY 14 DAY 1 MONTH 3 MONTHS 6 MONTHS | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To evaluate & compare the effect on jaw function (mouth opening, lateral movement, protrusive movements) of Temporomandibular joint derangement patients in oral nutraceutical ( collagen + sodium hyaluronate + curcumin + Boswellia + Piperine ) along with arthrocentesis and- iPRF versus arthrocentesis - iPRF alone . 2. To evaluate & compare the radiologic changes (MRI) in patients of Temporomandibular joint derangement treated with oral nutraceutical supplement ( collagen + sodium hyaluronate + curcumin + Boswellia + Piperine ) along with arthrocentesis & I-PRF versus arthrocentesis & I-PRF alone. 3. To evaluate & compare the quality of life in Temporomandibular joint derangement patients treated with oral nutraceutical supplement ( collagen + sodium hyaluronate + curcumin + Boswellia + Piperine ) along with arthrocentesis & iPRF versus arthrocentesis & iPRF alone .Timepoint: DAY 0 7 DAY 14 DAY 1 MONTH 3 MONTHS 6 MONTHS | — |
Countries
India
Contacts
Public ContactVaibhav Alone
All India Institute of Medical Sciences AIIMS - Jodhpur
Outcome results
None listed