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Understanding inflammatory markers in gum fluid and their role in gum disease

Association of Interleukin-35 levels in gingival crevicular fluid in periodontal health and disease: A comparative study - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/06/068425
Enrollment
66
Registered
2024-06-06
Start date
Unknown
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Non surgical periodontal treatment: Scaling and root planing with the help of ultrasonic scalers Total duration 0 days 3 months follow up Control Intervention1: Interleukin 35: Interleu

Sponsors

Radhika Singh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Subjects with age group between 25-60 years 2.Diagnosis of periodontal disease that is chronic periodontitis with probing pocket depth greater than 3 mm and Clinical attachment loss greater than 3 mm 3.Gingivitis that is patients showing clinical evidence of gingival inflammation but no CAL PPD of less than 3 mm and Gingival index score greater than 1 4. Periodontally healthy individuals that is showing no sign of clinical inflammation and periodontitis

Exclusion criteria

Exclusion criteria: 1.Systemic illnesses affecting periodontal disease. 2.Alcohol and tobacco consumers (in whatever form). 3.Females- pregnant or nursing. 4.Patient who has undergone periodontal treatment in six months back.

Design outcomes

Primary

MeasureTime frame
EFFECT OF NON-SURGICAL PERIODONTAL THERAPY ON IL-35 INCREASED OR DECREASED IN CHRONIC PERIODONTITISTimepoint: 0 DAYS AND 3 MONTHS

Secondary

MeasureTime frame
To explore the possibility of using IL-35 as a biomarker for periodontal disease activity.Timepoint: 3 MONTHS 0 DAYS

Countries

India

Contacts

Public ContactDr Akanksha Singh

Institute of dental sciences pilibhit byepass road Bareilly Uttar pradesh

akkisingh014@gmail.com7081222230

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026