Role of Platelet Rich Fibrin in healing of Pancreatic Anastomosis

Role of Platelet Rich Fibrin (PRF) in Pancreatico-Jejunostomy in patients undergoing Pancreatoduodenectomy – A Randomized Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/06/068400

Enrollment

Registered

2024-06-05

Start date

Unknown

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Platelet Rich Fibrin: Autologous Platelet Rich Fibrin wrapped around pancreatic anastomosis after reconstruction Control Intervention1: No Intervention: No Intervention Control Interven

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients undergoing pancreatico-duodenectomy for any indication 2. Good PRF Formation after centrifuge

Exclusion criteria

Exclusion criteria: 1. Pediatric patients 2. Non-consenting patients 3. Poor PRF formation

Design outcomes

Primary

Measure	Time frame
To compare the incidence of Post-operative Biochemical Leak (as per ISGPS Definition) after using PRF on PJ Anastomosis versus no interventionTimepoint: Post op Day 3	—

Secondary

Measure	Time frame
Difference in overall outcomes by length of hospital stay, ICU stay, complications, mortalityTimepoint: 3 months	—

Countries

India

Contacts

Public ContactDr Sudhindran S

Amrita Institute of Medical Sciences, Kochi

atishparikh@gmail.com9920028474

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026