A clinical trial to study the effects of Modified Atkins diet in patients with drug refractory epilepsy on standard medical therapy

Efficacy and tolerability of Modified Atkins diet in drug refractory epilepsy among adolescents and adults - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/06/068371

Enrollment

Registered

2024-06-05

Start date

Unknown

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G409- Epilepsy, unspecified

Interventions

Intervention1: Modified Atkins diet, Standard medical therapy: 3 months duration, Frequency of dietary intervention - All meals patient take during study period, Total carbohydrate content of 15-20 gr

Eligibility

Inclusion criteria

Inclusion criteria: Patients with Drug refractory epilepsy (as per ILAE definition) Patients who agree for regular follow up and ready to maintain seizure diary

Exclusion criteria

Exclusion criteria: Previous dietary intervention Medical illness incompatible with intervention Pregnant or lactating woman Patients being evaluated for epilepsy surgery Clinical suspicion of inborn errors of metabolism Patients who defer consent

Design outcomes

Primary

Measure	Time frame
Seizure frequency Adverse effects of diet Timepoint: 3 months	—

Secondary

Measure	Time frame
Quality Of Life In Epilepsy - Problems (QOLIE 10 P) IndexTimepoint: 3 months	—

Countries

India

Contacts

Public ContactDr Parampreet S Kharbanda

PGIMER, Chandigarh

neuroparam@hotmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026