Impact of antioxidant cocktail in transfusion dependent beta thalassemia

Impact of antioxidant cocktail in treatment of transfusion dependent beta thalassemia - nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/06/068355

Enrollment

Registered

2024-06-05

Start date

Unknown

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D561- Beta thalassemia

Interventions

Intervention1: beta thalassemia major: antioxidant cocktail - oral route Vit-E 400 IU/day, 200mg/day N Acetyl cysteine 50mg/kg/day Deferiprone this will be given for 1 year Control Intervention1: be

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age between 1-18 years 2. Hb concentration 4–9g/L

Exclusion criteria

Exclusion criteria: Major congenital anamolies child will be excluded

Design outcomes

Primary

Measure	Time frame
1.Hb level 2. Blood transfusion numbers in a year 3. changes in liver enzymesTimepoint: baseline after 3 months then at 6th month then at 9th month then finally after 1 year	—

Secondary

Measure	Time frame
changes in coagulation profileTimepoint: baseline at 6months at 1 year	—

Countries

India

Contacts

Public ContactDr Surendra singh

Shyam shah medical college

drsuansh@gmail.com7024968393

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026