Effect of Intraperitoneal Insertion of Ropivacaine on Perioperative Peak Expiratory Flow Rate (PEFR) in Patients Undergoing Elective Laparoscopic Cholecystectomy under General Anaesthesia

Effect of Intraperitoneal Instillation of Ropivacaine on Perioperative Peak Expiratory Flow Rate (PEFR) in Patients Undergoing Elective Laparoscopic Cholecystectomy under General Anaesthesia – A randomized, prospective, double blind study - Nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/06/068315

Enrollment

100

Registered

2024-06-04

Start date

Unknown

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Ropivacaine 0.5% 20ml: Group R patients will receive 20 ml 0.5 % Ropivacaine intraperitoneally in the Gall Bladder Fossa prior to port closure Deflation of pneumoperitoneum will be don

Eligibility

Inclusion criteria

Inclusion criteria: Patient undergoing Elective laparoscopic cholecystectomy. ASA I-II

Exclusion criteria

Exclusion criteria: Patient having OSA. Patient having cardiopulmonary functional limitation patient having psychiatric illness. Emergency surgery surgical duration less than 1hour & more than 3hours patient with BMI of more than 30 kg/m2

Design outcomes

Primary

Measure	Time frame
To compare perioperative PEFR in patients undergoing laparoscopic cholecystectomy under general anaesthesia with and without intraperitoneal instillation of 20 ml of 0.5% Ropivacaine. Timepoint: at 2hour , 6 hour , 12 hour , 24 hour	—

Secondary

Measure	Time frame
To find the time to first rescue analgesic in both groups. Timepoint: within 24h	—

Countries

India

Contacts

Public ContactDr. Koshy Verghese

Tata main hospital

himanshu.kumar@tatasteel.com7763807104

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026