Health Condition 1: K760- Fatty (change of) liver, not elsewhere classified
Conditions
Interventions
Intervention1: Group b-millets diet: This group would receive standard nutritional counselling, customized diet providing 20-25 Kcal/Kg and 1.0 gm protein/kg ideal body wt/day. 15-20% of the total cal
Sponsors
ICAR-IIMR
Eligibility
Inclusion criteria
Inclusion criteria: 1. Recently diagnosed consenting adults with NAFL (steatotosis) of any grade with or without features of metabolic syndrome
Exclusion criteria
Exclusion criteria: Individuals who had been hospitalised with complications of Diabetes mellitus, Chronic Kidney disease, Hypertension in the previous 6 months Those with intake of antibiotics within last month Seriously ill and bed ridden patients Patients with viral hepatitis Pregnant & lactating women Patients with significant alcohol consumption Patients having chronic inflammatory bowel disease or any chronic and autoimmune diseases will be excluded Patients with NAFLD with associated hypertriglyceridemia that requires administration of statins
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in hepatic steatosis as assessed by fibroscan, ultrasound (change in the CAP, LSM)Timepoint: 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in blood sugar as assessed by blood fasting glucose, serum insulin & HbA1cTimepoint: 3 months;Change in gut microbiotaTimepoint: 3months;Change in lipid parameters as assessed by blood lipid profile testTimepoint: 3 months;Change in liver enzymes as assessed by liver function testsTimepoint: 3 months;Change in Nutritional status as assessed using bioelectrical impedence analysisTimepoint: 3 months | — |
Countries
India
Contacts
Public ContactDr Jaya Joy Benjamin
Institute of Liver & Biliary Sciences
Outcome results
None listed