Skip to content

Effectiveness of propolis tiny particles placed in gums of patients with gum disease.

Evaluation of clinical efficacy of sub-gingivally delivered Propolis Nanoparticle as an adjunct to non-surgical periodontal therapy in patients with stage 2 and stage 3 periodontitis: a split mouth randomized controlled trial - NIL

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/06/068305
Enrollment
25
Registered
2024-06-04
Start date
Unknown
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Propolis nanoparticles solution.: All patients with stage 2 and stage 3 periodontitis will be treated with scaling and root planing followed by subgingival delivery of propolis nanopart

Sponsors

TPCTs Terna Dental college
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Both male and female patients with stage 2 or stage 3 periodontitis in at least 2 teeth in contralateral quadrants.2.Age group between 18-60 years with good systemic health.3. Minimum 20 teeth should be present in the mouth of patients. 4.Patients with no history of allergies.

Exclusion criteria

Exclusion criteria: 1.Patients suffering from any known systemic diseases.2.Smokers and alcoholic patients.3 Pregnancy or lactating female patients.4.Patients who have received surgical or nonsurgical periodontal therapy in last 3 months prior to the baseline visit.5.• Patients who have allergic to propolis products.

Design outcomes

Primary

MeasureTime frame
To evaluate the clinical efficacy of sub-gingivally delivered Propolis Nanoparticles as an adjunct to non-surgical periodontal therapy in patients with stage 2 and stage 3 periodontitis: a split mouth randomised controlled trial.Timepoint: Baseline one month after local drug delivery Three month after local drug delivery

Secondary

MeasureTime frame
To evaluate improvement in plaque index, gingival index, sulcular bleeding index, probing pocket depth and relative attachment lossTimepoint: Plaque index, gingival index, sulcular bleeding index, probing pocket depth and relative attachment loss will be evaluated at baseline, one month and three month.

Countries

India

Contacts

Public ContactDr Komal Shrikhande

Terna dental college and Hospital

desaiankit_2000@yahoo.com9920789319

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026