Health Condition 1: C719- Malignant neoplasm of brain, unspecified
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: All new onset glioma patients admitted for surgery in Neurosurgery IPD of G.I.P.M.E.R with clinical and radiological evidence of glioma preoperatively and histopathologically proven cases postoperatively.
Exclusion criteria
Exclusion criteria: 1. Patients who have received treatment such as radiotherapy and/or chemotherapy preoperatively will be excluded. 2. Patients with any history of other systemic malignancies will be excluded. 3. Patients with history of Alzheimer’s disease will be excluded. 4. Patients with history of recurrent glioma with multiple surgeries will be excluded. 5. All biopsy negative brain tumors for glioma postoperatively will be excluded from the case population and will be considered as a control population.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean expression of whole blood miRNA-128 in glioma cases and controls.Timepoint: 6 MONTHS | — |
Secondary
| Measure | Time frame |
|---|---|
| 1 Mean expression of whole blood miRNA-128 in glioma patients preoperatively and postoperatively Timepoint: 1 year;Association of mean expression of whole blood miRNA-128 with WHO grading & radiological findings of glioma.Timepoint: 1 year | — |
Countries
India
Contacts
Maulana Azad Medical College