Health Condition 1: I699- Sequelae of unspecified cerebrovascular diseases
Conditions
Interventions
Intervention1: Real tDCS + Real Piezoelectric glove + conventional physiotherapy: In this arm, real interventions with both tDCS and Piezoelectric gloves will be given for maximum of 1 month (5 days a
Sponsors
Indian Council of Medical Research
Eligibility
Inclusion criteria
Inclusion criteria: Age 18-75 years Chronic stroke (3 months-48 months Ischemic/Hemorrhagic stroke Patient should be conscious, coherent, comprehendible, cooperative Upper limb paresis Clinical evaluation: Mini- Mental Scale (MMSE:24-30) MRC: 1-3 Modified Ashworth Scale (1-3) All patients dwelling within 100km range from Delhi / NCR
Exclusion criteria
Exclusion criteria: History of seizures Recurrent stroke Severe psychiatric or cognitive impairment Contraindications to MRI or tDCS Progressive systemic diseases Not willing to consent Aphasia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in FMA score at 1 month from baselineTimepoint: Change in FMA score at 1 month from baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| Action research arm test (ARAT) 1,3,6 and 12 monthsTimepoint: 1,3,6 and 12 months;Brunnstrom stage of recovery 1,3,6 and 12 monthsTimepoint: 1,3,6 and 12 months;Change in FMA score at 1 yr from baselineTimepoint: 1 year;Change in FMA score at 3 months from baselineTimepoint: 3 months;Change in FMA score at 6 months from baselineTimepoint: 6 months;fMRI indices BOLD & DTI measures; FA; LI; CST integrityTimepoint: 1, 3, 6 and 12 months;modified Barthel Index (mBI) 1,3,6 and 12 monthsTimepoint: 1,3,6 and 12 months;Quality of Life Scale (SS-QOL) questionnaireTimepoint: 1, 3, 6 and 12 months;Serum BDNF will be estimated at baseline, 4 weeks, 3months, 6 months and 1 year of treatment.Timepoint: Baseline, 4 weeks, 3months, 6 months and 1 year | — |
Countries
India
Contacts
Public ContactVISHNU V Y
AIIMS New Delhi
Outcome results
None listed