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Comparing antibacterial action and in-between appointment pain of 3% sodium hypochlorite as root canal irrigant at different temperatures in necrotic teeth.

Comparative evaluation of antimicrobial efficacy and Inter-appointment pain with 3% sodium hypochlorite at different intracanal temperatures in teeth with Pulp necrosis with Symptomatic Apical periodontitis- A Randomized Clinical Study - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/06/068268
Enrollment
45
Registered
2024-06-03
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K041- Necrosis of pulp

Interventions

Intervention1: 3% Sodium Hypochlorite at temperature of 2°C: To evaluate the anti-microbial efficacy and inter-appointment pain of 3% sodium hypochlorite as root canal irrigant at a temperature of 2°C

Sponsors

Dr Shreya Volety
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Healthy patients (Category: American Society of Anesthesiologists class 1) (ASA House of Delegates 2014) aged between 18 – 60 years of age with teeth diagnosed with pulp necrosis with symptomatic apical periodontitis. 2. Necrotic pulps as confirmed by negative response to sensitivity pulp tests. 3. Teeth with symptomatic apical periodontitis 4. Teeth with or without periapical radiolucency size less than 2 mm. 5. A written informed consent will be obtained from all the patients and only those Patients who are ready to sign the consent form will be included in the study

Exclusion criteria

Exclusion criteria: Patients suffering from a significant systemic condition. 2. Patients who received antibiotic therapy within the previous 3 months 3. Teeth with calcified pulp chamber 4. Teeth that had received previous endodontic treatment 5. Cases showing periodontal pockets deeper than 4mm. 6. Patients on medications such as chemotherapy, anticoagulants, corticosteroids, bisphosphonates and immunosuppressant drugs

Design outcomes

Primary

MeasureTime frame
The outcome of this study will help us to know about the antimicrobial efficacy of 3% sodium hypochlorite at different temperatureTimepoint: baseline, 6hrs, 12hrs, 24hrs, 48hrs

Secondary

MeasureTime frame
To know about the inter-appointment pain of Triphala versus 3% sodium hypochlorite as root canal irrigant in teeth with necrotic pulpTimepoint: within 7 days

Countries

India

Contacts

Public ContactDr Ajay Singh Rao

K.M Shah Dental college and hospital

drajayinendo@gmail.com838501730

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026