Comparison between two drugs for sedation in endoscopic procedures.

Sedation in upper GI endoscopic procedures A comparison between propofol and dexmedetomidine - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/06/068267

Enrollment

Registered

2024-06-03

Start date

Unknown

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Administration of dexmedetomidine: Administration of intravenous dexmedetomidine given initially with a loading dose of 1mcg/kg for 6-10 minutes followed by maintenance dose of 0.2-1.4m

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients between 18 to 60 years either gender. Patients undergoing therpeutic upper GI endoscopies. No major comorbidity.

Exclusion criteria

Exclusion criteria: Patients refusing consent. Patients with major cardio respiratory comorbidities. Obesity. Hypersensitivity to study drugs. Previously failed upper GI endoscopic procedures. Patients with ongoing upper GI bleed. Patients with airway abnormalities.

Design outcomes

Primary

Measure	Time frame
Intravenous dexmedetomidine can be a suitable alternative for sedation in comparison to intravenous propofol.Timepoint: During Upper GI endoscopic procedures.	—

Secondary

Measure	Time frame
Assessment of peri procedural hemodynamic stability in upper GI endoscopic procedures while using intravenous dexmedetomidine & intravenous propofol.Timepoint: During Upper GI endoscopic procedures.;Assessment of peri procedural obtundation of airway reflex in upper GI endoscopic procedures while using intravenous dexmedetomidine & intravenous propofol.Timepoint: During Upper GI endoscopic procedures.	—

Measure

Time frame

Assessment of peri procedural hemodynamic stability in upper GI endoscopic procedures while using intravenous dexmedetomidine & intravenous propofol.Timepoint: During Upper GI endoscopic procedures.;Assessment of peri procedural obtundation of airway reflex in upper GI endoscopic procedures while using intravenous dexmedetomidine & intravenous propofol.Timepoint: During Upper GI endoscopic procedures.

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Countries

India

Contacts

Public ContactArnab Roy

Institute Of Post Graduate Medical Education and Research Kolkata

g.tapas@gmail.com8282801572

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026