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To compare the impact of two different anaesthetic agents on diameter of the Optic Nerve Sheath during Laparoscopic Surgeries.

An Open Labelled Randomized Controlled Trial to compare the effect of Desflurane and Target Controlled Infusion of Propofol on Optic Nerve Sheath Diameter in patients undergoing Laparoscopic Procedures - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/06/068231
Enrollment
110
Registered
2024-06-03
Start date
Unknown
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Effect of Desflurane on optic nerve sheath diameter in patients undergoing laparoscopic surgeries.: After tracheal intubation, anaesthesia will be maintained with Desflurane within the

Sponsors

Bharati Vidyapeeth (Deemed to be) University Medical College, Pune
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of ASA I, II, in the group of 18-60 years, posted foe elective laparoscopic surgeries under general Anaesthesia

Exclusion criteria

Exclusion criteria: Patient refusing for the study Patients with existing neurological diseases eye disease like glaucoma, lens opacity or trauma. Pre- existing raised ICP History of Craniotomy Pregnancy, breast feeding patients

Design outcomes

Primary

MeasureTime frame
To compare the effect of Desflurane and Target Controlled Infusion of Propofol on Optic Nerve Sheath Diameter in patients undergoing Laparoscopic surgeries.Timepoint: ONSD will be measured in both the groups of patients after induction, 10 min,1 hour, 2 hour, 3 hour after Co2 insufflation and final reading will be taken after desufflation.

Secondary

MeasureTime frame
To correlate the change in Optic Nerve Sheath Diameter with End Tidal Carbon dioxide concentration (EtCo2)Timepoint: EtCo2 will be measured along with ONSD after induction, 10 min, 1 Hour, 2 Hour, 3 Hour after CO2 insufflation and final reading will be taken after desufflation.

Countries

India

Contacts

Public ContactDr Kalyani Nilesh Patil

Bharati Vidyapeeth University

kalyanish19@gmail.com9673400066

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026