A trial to study whether Buprenorphine an analgesic drug added to local anaesthetic Bupivacaine for blocking nerves supplying upper limb improves the quality of anaesthesia.

“A comparative study of Ultrasound guided Supraclavicular brachial plexus block using Bupivacaine alone and the combination of Bupivacaine and Buprenorphine in patients undergoing elective upper limb orthopaedic surgeries. ? - Nil

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/068217

Enrollment

Registered

2024-05-31

Start date

Unknown

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Combination of Bupivacaine and Buprenorphine: Supraclavicular brachial plexus block with 25ml of 0.25% Bupivacaine and 3µg/Kg of Buprenorphine once over 5 minutes Control Intervention1

Eligibility

Inclusion criteria

Inclusion criteria: 1. Assessed patients of ASA I and II status. 2. Both gender. 3. Normal biochemical and hematological parameters. 4. Age group between 20 -60years 5. Patients weighing 50-70 Kgs. 6. Mallampati score of I and II 7. No known neurological deficit 8. No local sepsis

Exclusion criteria

Exclusion criteria: 1. Patients who have not given consent. 2. Patients with anticipated difficult airway. 3. Neurological disorders 4. History of allergy to local anaesthetics 5. History of cardiovascular and respiratory disorders 6. Local bony deformities 7. History of bleeding disorders 8. Extremely obese patients

Design outcomes

Primary

Measure	Time frame
Onset of action is faster and duration of action is prolonged when Combination of Bupivacaine and Buprenorphine is used compared to Bupivacaine aloneTimepoint: 6 to 7 hours	—

Secondary

Measure	Time frame
Post operative analgesia is prolonged when combination of Bupivacaine and Buprenorphine are usedTimepoint: 2to 3 hours	—

Countries

India

Contacts

Public ContactAnusha Dhage

Gulbarga institute of medical sciences

Anudha.dhage@gmail.com9538404005

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026