A clinical trial to study the drop in oxygen concentration at the level of pharynx compared to oxygen concentration at the level of nostrils.

Comparison of pharyngeal oxygen concentration and delivered oxygen concentration during preoxygenation with High Flow Nasal cannula - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/068206

Enrollment

Registered

2024-05-31

Start date

Unknown

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: High Flow Nasal cannula preoxygenation: providing oxygen with High Flow Nasal cannula starting from a flow rate of 10L upto 60L Intervention2: NIL: NIL Intervention3: oxygenation: Oxyge

Eligibility

Inclusion criteria

Inclusion criteria: 1.Age 18-60 year 2.ASA Physical status class I & II 3.Patients undergoing oro-tracheal intubation under general anaesthesia 4.expected duration of surgery of more than one hour

Exclusion criteria

Exclusion criteria: 1.Patients with existing respiratory illness 2.Pregnant patients 3.Patients with gross facial anomalies 4.Patients with any nasal or nasopharyngeal mass

Design outcomes

Primary

Measure	Time frame
To compare the highest pharyngeal FiO2 with delivered FiO2 .Timepoint: One hour before starting of general anesthesia.	—

Secondary

Measure	Time frame
To find association between nasal patency & change in FiO2 during HFNO preoxygenation.Timepoint: Will be done before the patient gets shifted inside the operation theatre at preoperative holding area.;To find association between set flow rate & change in FiO2 during HFNO preoxygenation.Timepoint: The flow rate will be increased at increments of 10L upto 60L, each flowrate given during a period of one minute.	—

Measure

Time frame

To find association between nasal patency & change in FiO2 during HFNO preoxygenation.Timepoint: Will be done before the patient gets shifted inside the operation theatre at preoperative holding area.;To find association between set flow rate & change in FiO2 during HFNO preoxygenation.Timepoint: The flow rate will be increased at increments of 10L upto 60L, each flowrate given during a period of one minute.

—

Countries

India

Contacts

Public ContactDr. Saveetha Priya M.G

JIPMER , Puducherry

jipmervasu@gmail.com9894444102

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026