Comparative Evaluation of Effectiveness of DFDBA Bone graft with Titanium Platelet Rich Fibrin (T-PRF) and Autologous Dentin Graft (ADG) with T-PRF in socket preservation after extraction

Comparative Evaluation of Effectiveness of Demineralized Freeze-Dried Bone Allografts (DFDBA) with Titanium Platelet Rich Fibrin (T-PRF) and Autologous Dentin Graft (ADG) with T-PRF in Alveolar Socket Preservation: A Randomised Control Trial. - nil

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/068192

Enrollment

Registered

2024-05-31

Start date

Unknown

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified

Interventions

Intervention1: Test group- Autogenous dentin graft with T-PRF: Intervention : ADG + T-PRF in test group Control Intervention1: Control group - of Demineralized Freeze-Dried Bone Allografts (DFDBA) wit

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients indicated for implant following extraction. Because of reasons like, fracture of root, failure of endodontic treatment, resorption (internal and external), over-retained primary teeth, non-restorable carious lesions, residual roots. 2) A complete mouth plaque score of less than 25% indicates good oral hygiene. 3) Existence of a natural tooth in opposition 4) Adjacent teeth presence 5) Thick gingival biotype 6) The clinical and radiological appearance of the unbroken alveolar bone walls 7) 4 mm of bone radiographically at root apex 8) D-1, D-2 or D-3 bone quality.

Exclusion criteria

Exclusion criteria: 1. Patients with impaired systemic health that would interfere with the process involved with repair and healing of bones e.g. (Diabetes mellitus, Osteoporosis, Blood disorders, and Titanium allergy). 2. Significant differences in maxilla-mandibular space. 3. Presence of para functional habits such as bruxism or clenching. 4. Presence of proclined teeth, teeth with interdental spacing, rotated or mal-aligned anterior teeth. 5. History of alcoholism, excessive smoking or drug abuse. 6. D-4 bone quality. 7. Radiotherapy and chemotherapy history. 8. Debilitating tempro-mandibular joint pathosis. 9. Untreated dental diseases. 10. Pregnant and lactating mothers.

Design outcomes

Primary

Measure	Time frame
radiographic analysis, we will access new bone formation, change in sockets vertical alveolar boneTimepoint: four months post operatively	—

Secondary

Measure	Time frame
The main results are linear phenotypic dimensional changes, at baseline & four months after healing at two locations in the midfacial & midpalatal bone & soft tissue thickness.Timepoint: After four months of surgery	—

Countries

India

Contacts

Public ContactShivani Prafulla Thakre

Sharad Pawar Dental College, Sawangi (Meghe)

pavbajaj@gmail.com8412045019

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026