Health Condition 1: E10- Type 1 diabetes mellitus Health Condition 2: E102- Type 1 diabetes mellitus with kidney complications Health Condition 3: E11- Type 2 diabetes mellitus Health Condition 4: E112- Type 2 diabetes mellitus with kidney complications
Conditions
Interventions
Intervention1: Hydroxychloroquine: Hydroxychloroquine tablet is given at a dose of 200mg twice a day after food for 6 months.
Control Intervention1: Placebo: Multivitamin tablets of similar size, shap
Sponsors
Dr Varun Kumar Bandi
Eligibility
Inclusion criteria
Inclusion criteria: Presence of Diabetic Nephropathy
Exclusion criteria
Exclusion criteria: 1. Pregnant Women 2. People not consenting for study 3. Participation in any other clinical trial 4. History of intolerance to study drug 5. Patients with history of cardiac arrhythmias or prolonged QT interval 6. Patients with severe retinopathy 7. Patients requiring in-patient admission at time of enrolment 8. Any other condition which in the opinion of the investigator, would put the safety of the participant at risk, impede compliance or hinder completion of the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Change in proteinuria 2. Change in estimated glomerular filtration rateTimepoint: 12 weeks, 24 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Effect of hydroxychloroquine on glycemic control 2. Effect of hydroxychloroquine on lipid profileTimepoint: 6 months | — |
Countries
India
Contacts
Public ContactVarun Kumar Bandi
Dr. Pinnamaneni Siddhartha Institute of Medical Sciences
Outcome results
None listed