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Antimicrobial efficacy of three different intracanal Endodontic medications.

Comparative Evaluation of three differ-ent intracanal medicaments for antimi-crobial efficacy in single rooted teeth with Pulp Necrosis and Asymptomatic Apical periodontitisâ??A Randomized double-blinded Clinical Study - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/05/068117
Enrollment
75
Registered
2024-05-30
Start date
Unknown
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified

Interventions

Intervention1: Angelus Bio-C Temp: Angelus Bio-C Temp is a ready-to-use bioceramic tricalcium silicate paste for intracanal dressing. Bio-C Temp (Angelus, Paraná, Brazil) is the first calcium-silicat

Sponsors

Dr Bhandary Vidula Vijay
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Systemically healthy patients (Category: American Society of Anaesthesiologists class 1) (ASA House of Delegates 2014)31 between age group of 18-60 years with maxillary or mandibular single rooted necrotic teeth with radiographic and clinical evidence of asymptomatic apical periodontitis will be included in the study. 2. Teeth with necrotic pulps confirmed clinically by pulp sensitivity tests will be included. 3. Patients having no previous history of endodontic treatment will be included. 4. Patients having periapical lesions with a periapical index score of 2 and above (Ã?rstavik et al. 1986) will be included 5. A written informed consent will be taken from all the patients and only those patients ready to sign the consent form will be included in the study

Exclusion criteria

Exclusion criteria: 1. Medically compromised patients will be excluded. 2. Patients who have received NSAIDs or antibiotic treatment in the three months before the study will be excluded. 3. Teeth with completely obliterated canals will be excluded. 4. Teeth with evidence of sinus tracts, pus discharge and weeping canals will be excluded. 5. Cases showing periodontal pocket depth deeper than 4mm will be excluded. 6. Teeth with open apex, root resorption or complex root canal anatomy will be excluded. 7. Teeth with developmental anomalies will be excluded. 8. Teeth with vertical root fractures, cracks will be excluded. 9. Pregnant and lactating women will be excluded.

Design outcomes

Primary

MeasureTime frame
Comparative evaluation of reduction of colony forming units in the intervention, comparator and control groups.Timepoint: Baseline(day of initiation of treatment) 7th day

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactDr Dexter Brave

K M Shah Dental College And Hospital

sanctus002@gmail.com9833048365

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Sep 19, 2026