A clinical trial to study the effect of collagen supplement on chronic periodontitis patient and on nitrtic oxide level in the saliva.

A clinico biochemical study to evaluate the efficacy of collagen peptide supplements with an intervention of nonsurgical periodontal therapy and on salivary nitric oxide level in chronic periodontitis. - Nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/068104

Enrollment

Registered

2024-05-30

Start date

Unknown

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Collagen peptide supplement: Systemically daily once 5 gram for 2 months Control Intervention1: without collagen supplement: without collagen supplement

Eligibility

Inclusion criteria

Inclusion criteria: Minimum 20 natural teeth Diagnosis: Chronic mild to moderate periodontitis Probing depth: 3-7mm Clinical Attachment Loss: 2-4mm Bleeding on probing Systemically healthy patients Patient agreed to give the consent only are included

Exclusion criteria

Exclusion criteria: Tobacco-smokers, electronic cigarette users, smokeless tobacco product users, alcohol users. Individuals that had used antibiotics and/or steroids within the past 3-month. Individuals with any systemic diseases. Lactating and/or pregnant females. Completely edentulous individuals

Design outcomes

Primary

Measure	Time frame
Decrease in periodontal probing depth and clinical attachment loss Timepoint: Baseline Four weeks Eight weeks	—

Secondary

Measure	Time frame
Decrease in the level of salivary nitric oxide Timepoint: Baseline Four weeks Eight weeks	—

Countries

India

Contacts

Public ContactDr Prashanth Shetty

Yogita dental college and hospital

drprashanthshetty3@gmail.com9886191999

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026