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To compare effects of Yoga and Pulmonary Rehabilitation in patients with Interstitial lung disease and examine their molecular mechanisms

To explore the effects of Yoga and Pulmonary Rehabilitation in patients with Interstitial lung disease and examine their molecular basis. - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/05/068088
Enrollment
114
Registered
2024-05-30
Start date
Unknown
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J848- Other specified interstitial pulmonary diseases

Interventions

Intervention1: Pulmonary Rehabilitation: Pulmonary Rehabilitation: Pulmonary rehabilitation (PR) program will include breathing retraining, exercise training, education sessions on disease information

Sponsors

Central Council for Research in Yoga and Naturopathy
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All participants must have quit smoking at least eight weeks before inclusion into the study. Patients with a clinical diagnosis of moderate to severe interstitial lung disease (ILD) having diagnosis of either Sarcoidosis or Hypersenstivity Pneumonitis (HSP) or Idiopathic Pulmonary Fibrosis (IPF) requiring enrollment into pulmonary rehabilitation program for their disease management.

Exclusion criteria

Exclusion criteria: 1.Patients having co-morbidities likely to affect the study parameters like pulmonary artery hypertension, Obesity hypoventilation, any other concomitant respiratory disease etc. 2.Patients having exercise intolerance due to heart failure, angina pectoris. 3.Endocrinal disorders such as Diabetes mellitus, thyroid disorder that is likely to cause autonomic dysfunction. 4.Patients having episode of acute infection in the month preceding induction into the study or during the study period. 5.Co-morbidities, which make yoga training impossible. 6.Those with complaints of intermittent claudication / varicose veins and Deep Vein Thrombosis.

Design outcomes

Primary

MeasureTime frame
Following parameters will be measured after providing Yogic exercises and Pulmonary rehabilitation: 1. Functional exercise capacity and 2. Health Related Quality of Life.Timepoint: Assessment of outcome parameters will be done at time of enrollment and 10 weeks after intervention, which will be either Pulmonary Rehabilitation or Pulmonary Rehabilitation along with specified Yogic exercsies

Secondary

MeasureTime frame
Following parameters will be measured: 1. Pulmonary functions with diffusion. 2. Cardiac autonomic function. 3. Body composition analysis 4. Molecular pathways including inflammatory markers, peripheral Phosphatidylcholine pathways, mitochondrial metabolic pathways, hypoxia response pathways and oxidative balanceTimepoint: Before and after 10 weeks of intervention

Countries

India

Contacts

Public ContactDr Vishal Bansal

V P Chest Institute

drvishalbansal@hotmail.com27402406

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026