Health Condition 1: G969- Disorder of central nervous system, unspecified Health Condition 2: O- Medical and Surgical
Conditions
Interventions
Intervention1: Sugammadex: Group S will be administered Sugammadex .
Dose -2mg/kg
frequency - once
route of adminstration -Intravenous
total duration of such intervention - 24hours
Control Intervent
Sponsors
Jawaharlal Nehru Medical CollegeDatta Meghe Institute of Higher Education and Research
Eligibility
Inclusion criteria
Inclusion criteria: a. Inclusion Criteria: 1. Consenting adults, undergoing elective intracranial tumor surgery under general anaesthesia with Vecuronium-induced neuromuscular blockade. 2.Adult patient above age of 18yrs -65yrs 3.No comorbidity 4.GCS –15/15
Exclusion criteria
Exclusion criteria: 1.Patients with contraindications to Sugammadex or Neostigmine 2.Pre-existing neuromuscular disorders 3. Those requiring prolonged postoperative ventilation. 4.Malignant hyperthermia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time taken for the reversal of neuromuscular blockade Timepoint: 1 hour | — |
Secondary
| Measure | Time frame |
|---|---|
| 2. Incidence of residual neuromuscular blockade post-reversal. 3. Recovery of neuromuscular function assessed via train-of-four ratio or similar monitoring methods. 4. Safety outcomes: Respiratory events, hemodynamic instability, and occurrence of cholinergic side effects. 5. Emergence from anesthesia and time to extubation. Timepoint: 1 hour | — |
Countries
India
Contacts
Public ContactAishwarya Nayak
Jawaharlal Nehru Medical College,Datta Meghe Institute of Higher Education and Research
Outcome results
None listed