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To Assess The Role of adjuvant intermittent theta burst stimulation over the right Dorsolateral Prefrontal Cortex in patients with alcohol use disorder compared with sham stimulation

Role of adjuvant Intermittent Theta Burst stimulation over right dorsolateral prefrontal cortex in patients with alcohol use disorders , a randomized double blind sham controlled trial - NIL

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/05/068023
Enrollment
60
Registered
2024-05-29
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F102- Alcohol dependence

Interventions

Intervention1: INTERMITTENT THETA BURST STIMULATION: Intermittent Theta Burst stimulation is applied over Right Dorsolateral Prefrontal Cortex in patients with alcohol use disorder , twice daily sessi

Sponsors

Institute Of Psychiatry A Centre Of ExcellenceIOPCOE
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. AGE OF PATIENT 18 TO 65 YRS IF AGE OF EITHER GENDER 2. Subjects who have given consent for participation in the study 3. Subjects meeting DSM V criteria for alcohol use disorder, not meeting criteria for dependence to other substances except for nicotine and caffeine. 4. Subjects whose last intake of alcohol will be within the past 2 weeks. 5. Subjects who are not suffering from psychosis , not in acute withdrawal state with CIWA AR score less than 10 and not suffering from delirium.

Exclusion criteria

Exclusion criteria: 1. Cognitive impairment 2. Current DSM V diagnosis of major depression , schizophrenia or any other psychotic disorder, or any other comorbid psychiatric illness . 3. Standard rTMS contraindications like history of epilepsy, metal implants near the head or in any part of the body , history of neurosurgical operations , pacemaker implant 4. Concurrent use of medications or drugs that are known to reduce the seizure threshold. 5. Pregnancy. 6. Subjects with intellectual disabilities

Design outcomes

Primary

MeasureTime frame
effect of intermittent theta burst stimulation in patients with alcohol use disorder on cravingTimepoint: DAY 7, 2 WEEKS ,4 WEEKS , 12 WEEKS

Secondary

MeasureTime frame
time to relapseTimepoint: within 3months of intervention

Countries

India

Contacts

Public ContactDr Suvrangshu Chattaraj

Maharaja Jitendra Narayan Medical College and Hospital

nikhilesmandal@gmail.com9531546172

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026