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Evaluation of pain & swelling with different irrigating solutions after removal of third molar

Evaluation of Clinical outcomes of Cold saline, Hydrocortisone and Normal saline as an irrigating solution during surgical removal of impacted mandibular third molars-A randomized control trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/05/067998
Enrollment
84
Registered
2024-05-28
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K011- Impacted teeth

Interventions

Intervention1: Hydrocortisone diluted in Normal Saline: Patients will receive 500 mg hydrocortisone diluted in 250 ml of normal saline as a irrigating solution during Surgical extraction of impacte

Sponsors

Dr Pranjal Rathi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients belonging to the age category of 18 to 53 years. 2.Patients who have not used antibiotics antimicrobial or anti inflammatory drugs before surgery. 3.Patients with moderate surgical difficulty score on Pedersons index 4to6. 4.Patients with normal bleeding and clotting times 5.Patients who are nonsmokers.

Exclusion criteria

Exclusion criteria: 1.Patients who are not willing to participate in the study. 2.Patients with presence of any systemic disorders. 3.Patients with previous history of radiation therapy. 4.Patients with previous history of allergy to anesthetic agent used. 5.Pregnant or lactating female subjects.

Design outcomes

Primary

MeasureTime frame
•To evaluate and compare the postoperative edema, pain, trismus on using cold saline(2-8?c), hydrocortisone, and normal saline as an irrigating solution during surgical removal of impacted mandibular third molarTimepoint: 3rd and 7th day

Secondary

MeasureTime frame
To evaluate and compare the association of variables (age and sex) between groupsTimepoint: 3rd and 7th day

Countries

India

Contacts

Public ContactDr Shridhar D Baliga

KAHER KLE Vishwanath Katti Institute of Dental Sciences

pranjal.rathi.616@gmail.com8755238365

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026