Comparison of post-operative pain reducing effect of local anaesthetic drug (lidocaine) administration during surgery using two routes of administration(intraperitoneal instillation versus subserosal infiltration)in laparoscopic cholecystectomy.

Effect of intraperitoneal instillation versus subserosal infiltration of lidocaine on post-operative pain in laparoscopic cholecystectomy in a tertiary care hospital- A randomized controlled clinical trial - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/067991

Enrollment

120

Registered

2024-05-28

Start date

Unknown

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Subserosal infiltration of lidocaine: A fine laparoscopic needle(20G) will be used for infiltration of 5ml 1% lidocaine (preservative free) in anterior serosa of Calots triangle after v

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing elective laparoscopic cholecystectomy.

Exclusion criteria

Exclusion criteria: 1. Jaundice 2. Pregnancy 3. Complicated morbid anatomy or very difficult dissection(Nassar scale III,IV,V) 4. Gall bladder malignancy 5. Any deviation from the proposed process of laparoscopy cholecystectomy, including conversion to open cholecystectomy 6. Equipment failure affecting duration of surgery

Design outcomes

Primary

Measure	Time frame
Post-operative pain using visual analog scale (VAS).Timepoint: At 1 hour, 4 hours, 12 hours and 24 hours post-operatively.	—

Secondary

Measure	Time frame
1. Shoulder tip pain. 2. Post-operative nausea and vomiting (PONV).Timepoint: At 1 hour, 4 hour, 12 hours and 24 hours post operatively	—

Countries

India

Contacts

Public ContactDr Rajat

Sikkim Manipal Institute of Medical Sciences.

dr.k.nishant@gmail.com8670679466

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026