Comparison of antimicrobial efficiency of three different irrigating solutions in single rooted non vital teeth

Comparative evaluation of antimicrobial efficacy of Triton, nine percent HEDP and three percent Sodium Hypochlorite solution as a root canal irrigant in single rooted non vital teeth: A Randomized Double Blinded Clinical Study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/067990

Enrollment

Registered

2024-05-28

Start date

Unknown

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K041- Necrosis of pulp

Interventions

Intervention1: TRITON: The solution comprises two distinct parts: Part A includes chelators (CA), surfactants, pH modifiers, and stabilizers, while Part B contains 8% NaOCl and a pH modifier. Through

Eligibility

Inclusion criteria

Inclusion criteria: 1.Healthy patients (Category: American Society of Anaesthesiologists class 1) (ASA House of Delegates 2014) aged between 18 â?? 60 years of age will be included. 2.Maxillary or mandibular non vital single rooted teeth containing single canal . 3. Maxillary or mandibular teeth having Periapical Index (PAI)Score1 and 2 (according to PAI score classification) will be included. 4.Only those patients ready to sign the consent form will be included in the study.

Exclusion criteria

Exclusion criteria: 1.Teeth with open apex, root resorption and calcified pulp chamber and canals will be excluded from the study. 2.Teeth with curvature more than 20 degree (according to Schniederâ??s classification ) will be excluded from the study. 3.Teeth which had received previous endodontic treatment will be excluded from the study. 4.Pregnant and lactating mothers will be excluded from the study. 5.Teeth with developmental anomaly or pathology or congenital defects will be excluded. 6.Patient not ready to give the consent will be excluded from the study.

Design outcomes

Primary

Measure	Time frame
The result of the study helps us to know the antimicrobial efficacy of three diferent irrigating solutions which are triton,9% HEDP and 3% Sodium Hypochlorite Solution by taking pre and post irrigation samples and then after collection of samples assessing them by formation of growth of mean colony forming units.Timepoint: 48 to 72 hours from the day of collection of sample.	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr. Vishnu Pratap Singh Rathore

K.M. Shah Dental College And Hospital

dr.vishnurathore84@gmail.com7575071175

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Sep 19, 2026