Health Condition 1: J984- Other disorders of lung Health Condition 2: P220- Respiratory distress syndrome of newborn
Conditions
Interventions
Intervention1: Pressure control/Assist control mode of ventilation: In this mode there is delivery of a synchronized mechanical breath each time a spontaneous is detected (assist) or if patient fails
Sponsors
AIIMS Bhopal
Eligibility
Inclusion criteria
Inclusion criteria: 1. A preterm newborn requiring mechanical ventilation due to respiratory distress syndrome within 72 hours of birth.
Exclusion criteria
Exclusion criteria: 1.Surgical anomalies of chest/abdomen, 2.Major extra-thoracic malformation/syndromic newborns 3.Severe perinatal asphyxia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Duration of mechanical ventilation (mean days of ventilation) 2.Progression of respiratory failure and requirement of High-frequency ventilation Timepoint: hourly data collection till death or till discharge from the NICU | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Survival of preterm newborns who required invasive mechanical ventilation for primary respiratory distress syndrome. 2.Surfactant doses requirements 3.Extubation failure 4.Incidence of pneumothorax 5.Duration of non-invasive respiratory support 6.Progression to Bronchopulmonary dysplasia 7.Extrapulmonary morbidity of Retinopathy of prematurity, intraventricular haemorrhage, and patent ductus arteri 8.Need for sedation or worsening of clinical distress needing augmentation of pressure indicated by tachycardia,tachypnea and hypoxia which suggested inadequate ventilationTimepoint: hourly data collection till death or till discharge from the NICU | — |
Countries
India
Contacts
Public ContactDr Chetan Khare
AIIMS Bhopal
Outcome results
None listed