Health Condition 1: J441- Chronic obstructive pulmonary disease with (acute) exacerbation
Conditions
Interventions
Intervention1: NIL: NIL
Sponsors
None
Eligibility
Inclusion criteria
Inclusion criteria: Patients requiring hospital admission for ECOPD (moderate to severe)
Exclusion criteria
Exclusion criteria: 1. Patients with a known hematologic disease. 2. Pregnancy 3. Liver disease 4. Diabetic ketoacidosis 5. Acute stroke 6. Severe malnutrition 7. Refusal to consent for the study. 8. Patients refusing available treatment modalities advised by the physician including invasive mechanical ventilation, renal replacement therapy etc
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic profile and threshold of Red cell distribution width to albumin ratio (RAR) (at admission) that predicts 28-day all-cause mortality in patients admitted with ECOPD.Timepoint: Admission to 28-days post-admission or death, whichever is earlier | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood or component transfusionTimepoint: Admission to 28-days post-admission or death, whichever is earlier;Hospital mortalityTimepoint: Admission to 28-days post-admission or death, whichever is earlier;ICU complicationsTimepoint: Admission to 28-days post-admission, ICU discharge or death, whichever is earlier;ICU mortalityTimepoint: Admission to 28-days post-admission, ICU discharge or death, whichever is earlier;Length of hospital stayTimepoint: Admission to 28-days post-admission, hospital discharge or death, whichever is earlier;Length of ICU stayTimepoint: Admission to 28-days post-admission, ICU discharge or death, whichever is earlier;Need for invasive mechanical ventilationTimepoint: Admission to 28-days post-admission or death, whichever is earlier;Need for recurrent invasive ventilationTimepoint: Admission to 28-days post-admission or death, whichever is earlier;Need for renal replacement therapyTimepoint: Admission to 28-days post-admission or death, whichever is earlier;New onset bacteraemia/fungemiaTimepoint: Admission to 28-days post-admission or death, whichever is earlier;NIV failureTimepoint: Admission to 28-days post-admission, ICU discharge or death, whichever is earlier;Number of vasopressor free daysTimepoint: Admission to 28-days post-admission or death, whichever is earlier;Number of ventilator free daysTimepoint: Admission to 28-days post-admission or death, whichever is earlier;Organ failure free daysTimepoint: Admission to 28-days post-admission or death, whichever is earlier;SOFA, APACHE II, and CCI ScoreTimepoint: At Admission | — |
Countries
India
Contacts
Public ContactDr Gaurav Jain
All India Institute of Medical Sciences, Rishikesh
Outcome results
None listed