Comparision between different doses of isotretinoin in acne

Comparative therapeutic efficacy of different dosage regimens of oral isotretinoin in acne vulgaris. - Nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/067961

Enrollment

Registered

2024-05-28

Start date

Unknown

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L700- Acne vulgaris

Interventions

Intervention1: Oral isotretinoin: Oral isotretinoin 20mg once a day for 3 months Control Intervention1: Oral isotretinoin: Oral isotretinoin 20mg alternate day for 3 months Control Intervention2: Oral

Eligibility

Inclusion criteria

Inclusion criteria: All consecutive male and female patients of acne vulgaris ( grade 2 and above) involving the face who have not received any treatment in the past 4 weeks Patients between 16-50 years

Exclusion criteria

Exclusion criteria: Pregnant females , females planning pregnancy within the next 9 months , breastfeeding females immunosuppressed individuals known hypersensitivity to synthetic , natural vitamin A any systemic illness lasting more than 3 weeks deranged liver function tests and lipid profile reproductive age group females not willing to practice methods of contraception as advised

Design outcomes

Primary

Measure	Time frame
Grade of improvement in different regimensTimepoint: measured at baseline, week 4 , week 8 and week 12	—

Secondary

Measure	Time frame
adverse events of different dosage regimens of oral isotretinoin in acne vulgarisTimepoint: measured at baseline, week 4 , week 8 and week 12	—

Countries

India

Contacts

Public ContactDr Gurvinder Pal Thami

government medical college and hospital

thamigp@gmail.com9646121544

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026