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Evaluation of the analgesia obtained by radiofrequency ablation versus chemical neurolysis (phenol) of splanchnic nerve in the management of upper abdominal chronic pain.

Comparison of radiofrequency ablation versus chemical neurolysis (phenol) of splanchnic nerve in the management of chronic upper abdominal pain : A Randomised control trial - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/05/067936
Enrollment
50
Registered
2024-05-27
Start date
Unknown
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Radiofrequency ablation of Splanchnic nerve: Under fluroscopy guidance ,a metal forceps guide will be placed on participant’s body, strategically positioning it so that the forceps tip
s end-on appearance. The cannula is advanced with meticulous attention, ensuring a gradual and precise approach. Confirmation of the final placement occurred by examining a posteroanterior (PA) image,

Sponsors

Sridhar M
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)= 18 year of both sex who suffered from upper abdominal pain (visceral pain with VAS =4)for a duration of more than 3 months. 2)  Patients who were taking the maximum tolerable dose of opioids.  3) Splanchnic nerve accessible for bilateral neurolysis.

Exclusion criteria

Exclusion criteria: 1. Patient refusal, 2. Organ failure, 3. Coagulation disorders, 4. Local infection at the puncture site, 5. Sepsis, 6. Allergy to the contrast dye, 7. Pregnant women, 8. Psychiatric illness that affects cooperation

Design outcomes

Primary

MeasureTime frame
Change in pain NRS score from baseline to 3 months post intervention.Timepoint: Baseline , 7 days , 1 month , 3 month

Secondary

MeasureTime frame
Change in Analgesic requirement (medication quantification scale) from baseline to 3 months post intervention.Timepoint: Baseline , 7 days , 1 month , 3 month;Change in karnofsky performance status scale from baseline to 3 months post intervention.Timepoint: Baseline , 7 days , 1 month , 3 month;Change in sleep score from baseline to 3 months post intervention.Timepoint: Baseline , 7 days , 1 month , 3 month

Countries

India

Contacts

Public ContactDr Praveen Talawar

AIIMS Rishikesh

praveenrt64@gmail.com9654162941

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026