Health Condition 1: K801- Calculus of gallbladder with othercholecystitis Health Condition 2: K808- Other cholelithiasis
Conditions
Interventions
Intervention1: B Intranasal Nitroglycerine: Group B will receive dose of 800 mcg of intranasal nitroglycerine spray.
Control Intervention1: A Intranasal Nitroglycerine: Group A will receive dose of 40
Sponsors
Dr Shruti Panda
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age 18 to 60 yrs of either sex. 2.ASA Physical class I and II posted for elective laparoscopic cholecystectomy. 3.Individuals with BMI 19-28 kg/m2
Exclusion criteria
Exclusion criteria: 1.Systolic blood pressure less than 90 mm Hg. 2.Allergy to nitrates. 3.Patients who are on Phosphodiesterase Inhibitors, Antihypertensives or sympathomimetics 4.Patients with known nasal pathologies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the effect on Mean Arterial Pressure.Timepoint: T0 – 3 mins before pneumoperitoneum T1- At the time of pneumoperitoneum T2 – 2 mins after pneumoperitoneum T3 – Every 2 mins for first 10 mins T4- Every 15 mins till end of surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)Effect on SBP,DBP,HR at various time intervals 2)To study the incidence of PONV, headache. Timepoint: -T0 – 3 mins before pneumoperitoneum -T1- At the time of pneumoperitoneum -T2 – 2 mins after pneumoperitoneum -T3 – Every 2 mins for first 10 mins -T4- Every 15 mins till end of surgery | — |
Countries
India
Contacts
Public ContactDr. Ayesha Pattnaik
Kalinga Institute of Medical Sciences, Bhubaneswar
Outcome results
None listed