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To compare the dose of propofol required for induction in pediatric patients undergoing elective surgeries in two groups; one receiving dexmedetomidine nebulisation and other intravenous ketamine as premedications respectively.

Comparison of preoperative dexmedetomidine nebulisation and i.v. ketamine on the dose of propofol for induction in paediatric patients under General Anaesthesia: A Randomised Controlled Trial. - nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/05/067911
Enrollment
70
Registered
2024-05-27
Start date
Unknown
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Preoperative Dexmedetomidine Nebulisation: Patients will receive nebulization with dexmedetomidine using a nebulizer mask at the dose of 2 µg/kg, made to a volume of 4ml by using normal

Sponsors

All India Institute of Medical Sciences AIIMS Jodhpur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Pediatric patients belonging to the group of ASA I/II and in the age group of 3-8 years scheduled to undergo elective surgeries under General anesthesia

Exclusion criteria

Exclusion criteria: 1.Patients undergoing emergency surgeries. 2.Patients whose parents or legal guardians refuse to provide consent. 3.Patients with known or unanticipated difficult airway. 4.Patients with known allergy to dexmedetomidine. 5.Patients having preoperative hemodynamic instability such as shock.

Design outcomes

Primary

MeasureTime frame
To assess the effect of preoperative dexmedetomidine nebulisation on the dose of propofol required for induction under general anaesthesia.Timepoint: At baseline (at the time of induction)

Secondary

MeasureTime frame
To assess: 1. Hemodynamic responses (HR & BP) at the time of endotracheal intubation. 2. Parent separation anxiety among children. 3. Mask acceptance at the time of induction. 4. To note any complications.Timepoint: At Baseline

Countries

India

Contacts

Public ContactAbhinandan Kumar

Department of Anaesthesiology and Critical Care, AIIMS Jodhpur

drshilpagoyal@yahoo.com8003996880

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026