Health Condition 1: K040- Pulpitis Health Condition 2: R00-R99- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
Conditions
Interventions
Intervention1: Trypsin as Endodontic Irrigant: Trypsin, a proteolytic enzyme known for its anti-inflammatory and antioxidant properties, is recognized for reducing postoperative pain. 6ml of Trypsin (
Sponsors
Dr Megha N
Eligibility
Inclusion criteria
Inclusion criteria: Healthy individuals of age 18ââ?¬â??60 years Patients with symptomatic irreversible pulpitis. Patients with active pain (moderate-to-severe) in mandibular molars Patient with the ability to understand and use pain scales. Patient who accepts to enroll in the study
Exclusion criteria
Exclusion criteria: Uncooperative Patients, Pregnant and lactating patients, Mentally retarded Patient with a history of taking analgesics in the previous 12 hours prior to treatment, patient has more than one symptomatic mandibular tooth in the same quadrant, Patients having a history of allergies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Trypsin, when used as an endodontic irrigant, may prove to be effective for post-endodontic pain following single-visit root canal treatmentTimepoint: 6 , 12 , 24 and 48 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| Trypsin, when used as an endodontic irrigant, may prove to be more effective than placebo for post-endodontic pain following single-visit root canal treatmentTimepoint: 6, 12 ,24 and 48 hours | — |
Countries
India
Contacts
Public ContactDr X Nagamaheshwari
Army College of Dental Sciences
Outcome results
None listed