low dose ketamine for pain relief in CA breast patients for breast cancer surgery

Impact of intraoperative and post operative low dose ketamine infusion on neuropathic pain component in chronic persistent postsurgical pain following breast cancer surgery . A randomized controlled double blind study - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/067888

Enrollment

100

Registered

2024-05-24

Start date

Unknown

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C509- Malignant neoplasm of breast of unspecified site

Interventions

Intervention1: Group S-Injection Ketamine: Study group in which patients received 0.4mg/kg ketamine intravenous as bolus before skin incision followed by intraoperative and immediate postoperative int

Eligibility

Inclusion criteria

Inclusion criteria: Adult female patients between 18-65 year of age, who are diagnosed as carcinoma breast and scheduled to undergo elective breast cancer surgery

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
To assess and compare NRS-Pain scores and neuropathic pai. n in the study group S as compared to similar scores in control group C following breast cancer surgery at 1hour, 6 hours, 24 hours, 72 hours, 1 month, 2months and 3 months post-breast cancer surgery.Timepoint: To assess and compare NRS-Pain scores and neuropathic pain in the study group S as compared to similar scores in control group C following breast cancer surgery at 1hour, 6 hours, 24 hours, 72 hours, 1 month, 2months and 3 months post-breast cancer surgery.	—

Measure

Time frame

To assess and compare NRS-Pain scores and neuropathic pai. n in the study group S as compared to similar scores in control group C following breast cancer surgery at 1hour, 6 hours, 24 hours, 72 hours, 1 month, 2months and 3 months post-breast cancer surgery.Timepoint: To assess and compare NRS-Pain scores and neuropathic pain in the study group S as compared to similar scores in control group C following breast cancer surgery at 1hour, 6 hours, 24 hours, 72 hours, 1 month, 2months and 3 months post-breast cancer surgery.

—

Secondary

Measure	Time frame
To assess and compare rescue analgesia required in the study group S as compared to control group C following breast cancer surgery. To assess and compare SF12 scores in the study group S as compared to control group C following breast cancer surgery. 3To assess and compare adverse effects in the study group S as compared to control group C following breast cancer surgery. Timepoint: 1,6,24,72 hours 1,2,3 months	—

Measure

Time frame

To assess and compare rescue analgesia required in the study group S as compared to control group C following breast cancer surgery. To assess and compare SF12 scores in the study group S as compared to control group C following breast cancer surgery. 3To assess and compare adverse effects in the study group S as compared to control group C following breast cancer surgery. Timepoint: 1,6,24,72 hours 1,2,3 months

—

Countries

India

Contacts

Public ContactRajat Singh

University College of Medical Sciences/Guru Tegh Bahadur Hospital

profashoksaxena2@gmail.com9810431367

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026