Comparison of Two Drugs used during Recovery from General Anaesthesia for better outcome using special monitoring device.

Comparison of Sugammadex and Neostigmine/Glycopyrrolate in Reversing Neuromuscular Blockade in Adults Using Neuromuscular Monitor - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/067883

Enrollment

120

Registered

2024-05-24

Start date

Unknown

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis

Interventions

Intervention1: Sugammadex: 60 patients will be given single dose intravenous Sugammadex,2 mg/kg over a period of 1 minute at reappearance of the second bar of the TOF response after the last dose of r

Eligibility

Inclusion criteria

Inclusion criteria: 1. Adult patients undergoing elective laparoscopic surgery 2. American Society Of Anesthesiologists Grade 1 and 2 3. Patients giving Informed Written, Valid consent

Exclusion criteria

Exclusion criteria: 1. Patients age below 18 years and above 60 years 2. Patients with ASA Grade III and IV 3. Patients refusing consent 4. History of substance abuse and current opioid use 5. Pregnancy 6. Known allergy to anaesthetic drugs

Design outcomes

Primary

Measure	Time frame
To compare the efficacy of two reversal agents in reversing neuromuscular blockade induced by steroid group of non-depolarising muscle relaxants to facilitate better outcome after elective surgery.Timepoint: Train of Four(TOF) Ratio will be recorded during preoxygenation as baseline, 5 mins after intubation, 5 mins before giving reversal agent, 10 mins after giving reversal agent and 1 hour after giving reversal agent.	—

Measure

Time frame

To compare the efficacy of two reversal agents in reversing neuromuscular blockade induced by steroid group of non-depolarising muscle relaxants to facilitate better outcome after elective surgery.Timepoint: Train of Four(TOF) Ratio will be recorded during preoxygenation as baseline, 5 mins after intubation, 5 mins before giving reversal agent, 10 mins after giving reversal agent and 1 hour after giving reversal agent.

—

Secondary

Measure	Time frame
To compare how much time is required to completely reverse the patient from general anaesthesia using sugammadex or neostigmine as reversal agents.Timepoint: Train of Four(TOF) Ratio will be recorded after 1 hour of Reversal	—

Countries

India

Contacts

Public ContactDR Debjani Gupta

KPC Medical College and Hospital

debjani258@gmail.com9830071577

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026