Comparative study of efficacy of Prostaglandin F2A gel alone and mifepristone with ProstaglandinF2A gel as cervical ripening agent

Comparative study of efficacy of dinoprostone gel alone and mifepristone with dinoprostone gel as cervical ripening agent - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2024/05/067880

Enrollment

100

Registered

2024-05-24

Start date

Unknown

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O80- Encounter for full-term uncomplicated delivery

Interventions

Intervention1: Dinoprostone gel(PGF2A): Dose-0.5mg Route of administration- Per Vaginal Frequency-6 hrs interval Duration of therapy-total 3 doses Local application of prostaglandin E2 – dinoprostone

thus, it induces labor or allows the pregnancy to be terminated. Mifepristone is a potential method of inducing labor in late pregnancy through its action in antagonizing progesterone, thus increasing

Eligibility

Inclusion criteria

Inclusion criteria: Term singleton pregnancy in Cephalic Presentation with intact membrane with Bishop score less than 5

Exclusion criteria

Exclusion criteria: Any presentation other than cephalic, pregnancy with asthma, any contraindication to prostaglandins, previous uterine scars, multiple pregnancy

Design outcomes

Primary

Measure	Time frame
1.Bishop score after 6 hrs of 1st dose of diniprostone gel 2.Induction to delivery time 3.mode of delivery Timepoint: 12 months	—

Secondary

Measure	Time frame
1. APGAR score of neonate at birth & after 5min 2.PPH 3.hospital stay.Timepoint: 12 months	—

Countries

India

Contacts

Public ContactDr Charu Jain

Command Hospital Air Force, Bengalore

amitcharu0412@gmail.com9571330102

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026