Two different treatments methods with Platelet fibrin and Laser to see which one speeds up the process of moving canine teeth in orthodontic patients.

Comparison of platelet rich fibrin (PRF) and low-level laser therapy (LLLT) on rate of orthodontic tooth movement during canine retraction- A split-mouth randomized controlled trial.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/067851

Enrollment

Registered

2024-05-24

Start date

Unknown

Completion date

Unknown

Last updated

2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K088- Other specified disorders of teethand supporting structures

Interventions

Intervention1: Canine retraction: Canine retraction using niti closed coil spring on 0.018 AJ wilcock wire. Retraction measured at T0,T1,T2,T3,T4,T5. Study will complete in 56 days. Control Interventi

Eligibility

Inclusion criteria

Inclusion criteria: Presence of permanent dentition with mild crowding. Patients having Class I molar relationship bilaterally. Indication of extraction of 1st premolars bilaterally in the treatment plan. Good oral hygiene.

Exclusion criteria

Exclusion criteria: Previous orthodontic treatment Underlying periodontal disease or TMJ disorder Syndromic patient. Mixed dentition patients Missing or impacted tooth

Design outcomes

Primary

Measure	Time frame
Tooth movement increase,Timepoint: T0 On the day of extraction T1 7days after extraction T2 14 days after extraction T3 28 days after extraction T4 42 days after extraction T5 56 days after extraction	—

Secondary

Measure	Time frame
IL-1 beta appearance in Platelet rich fibrin and Low level laser siteTimepoint: T0 On the day of extraction T1 7days after extraction T2 14 days after extraction T3 28 days after extraction	—

Countries

India

Contacts

Public ContactDr Puja Priya

Bharati Vidyapeeth Deemed University Dental College and Hospital, Navi Mumbai,

dr.mishraharsh@gmail.com8451840579

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026