Use of oral tablet Tizanidine before giving ultrasound guided regional anaesthesia in adults undergoing upper limb surgeries to study how long after the surgery pain killer is required and extent of pain after surgery

The effect of Tizanidine premedication on block characteristics following ultrasound guided supraclavicular brachial plexus block in adults using Ropivacaine: a randomized controlled study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/067779

Enrollment

Registered

2024-05-21

Start date

Unknown

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Oral Tizanidine: Oral Tizanidine 4 mg will be given 60 mins before surgery under supraclavicular brachial plexus block using Ropivacaine Control Intervention1: Placebo: Oral placebo tab

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA I AND II physical status 2. Scheduled for surgery of upper extremity under supraclavicular brachial plexus block

Exclusion criteria

Exclusion criteria: 1. Patient refusal 2. Contraindications to regional anaesthesia like bleeding diasthesis, infection at site of block, peripheral neuropathy, coagulopathy 3. Known allergy to study medications 4. Concomitant use of sedatives or analgesics 5. Failed brachial plexus block

Design outcomes

Primary

Measure	Time frame
Time to first analgesia that is time to the first Tramadol dose administered post operative ( in mins )Timepoint: 2 h, 4h, 6h,8h, 12h, at discharge	—

Secondary

Measure	Time frame
POST OPERATIVE NRS SCORES, POST OPERATIVE TRAMADOL CONSUMPTION AND BLOCK RELATED COMPLICATIONSTimepoint: Post operative 0h, 2h, 4h, 6h, 8h, 12h, at discharge	—

Countries

India

Contacts

Public ContactPrakash Kumar Dubey

Indira Gandhi Institute of Medical Sciences

pkdubey@hotmail.com9430511851

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026