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Treatment of gum loss in gum disease individuals using animal derived membrane along with patients blood derived substances

Comparative evaluation of the clinical outcomes of xenogeneic pericardial collagen membrane enriched with two different forms of platelet concentrates in the treatment of gingival recession- A prospective study - NIL

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/05/067734
Enrollment
46
Registered
2024-05-21
Start date
Unknown
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K060- Gingival recession

Interventions

Intervention1: Group 1 Xenogeneic pericardial membrane impregnated with injectable platelet rich fibrin(XCM+i-PRF): The gingival recession sites will be treated with xenogeneic pericardial collagen me

Sponsors

kiran choudhary
Lead Sponsor
SRM Dental College
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1. Systemically healthy subjects with an age range of 18-65 years. 2. Individuals diagnosed with recession defects in maxillary anteriors and premolars (Cairo’s RT1 , RT2 classes of recession) 3. Sites with minimum depth of recession =2mm. 4. Isolated or multiple adjoining recession involving =3 teeth.

Exclusion criteria

Exclusion criteria: 1. Sites with probing pocket depth =4mm. 2.Teeth with mobility and/or associated with trauma from occlusion. 3. Sites with dental caries and prosthetic restorations. 4. Patients who exhibit unacceptable oral hygiene compliance during/or after phase ? therapy. 5. Smokers. 6. Pregnant and lactating women. 7.Patient known allergic response with equine derived substances. 8.Patients with known platelet disorders or using any medication that are known to interfere with platelet function. 9. Patients with systemic conditions or disease influencing the course of periodontal disease and therapy.

Design outcomes

Primary

MeasureTime frame
To assess and compare the changes in the recession height from baseline to 6 months, within and between the study groupsTimepoint: Baseline and 6months

Secondary

MeasureTime frame
1. To assess and compare the percentage of complete root coverage (CRC%) achieved at 6 months between the research groups 2.To assess and compare the patient perception regarding esthetics following the treatment modalities by using Visual Analogue Scale scores (VAS-E) Timepoint: 6months

Countries

India

Contacts

Public ContactDRANUPAMA TADEPALLI

SRM dental college

anupamamds@gmail.com9677065517

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026