Comparison of two different concentrations of Ropivacaine local anaesthetic for postoperative pain relief in abdominal hysterectomy surgeries

Comparison of Epidural Infusion of 0.1% Ropivacaine and 0.2% Ropivacaine for Postoperative Analgesia using Elastomeric Pump in Abdominal Hysterectomies - A Randomised Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/067730

Enrollment

100

Registered

2024-05-21

Start date

Unknown

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N926- Irregular menstruation, unspecified

Interventions

Intervention1: Epidural infusion of 0.1% Ropivacaine for postoperative analgesia: 0.1% Ropivacaine is given as continuous epidural infusion using elastomeric pump in postoperative day 1 and 2 at the r

Eligibility

Inclusion criteria

Inclusion criteria: 1.Elective surgeries with ASA Grading 1,2 and 3 2.Patients undergoing abdominal hysterectomy 3.Weight from 50kg to 80kg 4.Height from 145cm to 165cm

Exclusion criteria

Exclusion criteria: 1.Patient refusal 2.Allergic to Ropivacaine and Fentanyl 3.Local infection at the site of epidural injection 4.Coagulopathy 5.Hypovolemia 6.Patient on anticoagulant therapy 7.Uncooperative patients

Design outcomes

Primary

Measure	Time frame
To compare the VAS score at rest, movement and while coughing between the patients getting 0.1% and 0.2% ropivacaine as epidural infusion for pain reliefTimepoint: The time duration taken by the patient to complain of pain with VAS more than 3	—

Secondary

Measure	Time frame
To compare haemodynamic changesTimepoint: The time duration taken for mean arterial pressure to fall less than 60;To compare the motor blockadeTimepoint: The time duration taken by the patient to complain of lower limb numbness;To compare the need for rescue analgesiaTimepoint: The time duration taken by the patient to complain pain with VAS more than 5 even after giving rescue analgesia	—

Countries

India

Contacts

Public ContactM Karthik

SRM Medical College Hospital and Research Institute

drkarthik.cpt@gmail.com9994122396

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026