Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Tab melatonin 5 mg: Tab melatonin 5 mg will be given to 120 min before surgery in intervention group. Postoperative pain scores upto 24 hrs, will be monitored.
Control Intervention1: ta
Sponsors
AIIMS Raipur
Eligibility
Inclusion criteria
Inclusion criteria: -Adult patients aged 18-to-80 years -ASA grades II- to-III -Patients scheduled for elective on-pump cardiac surgery requiring median sternotomies such as coronary artery bypass grafting (CABG), CABG with or without valve replacement, and isolated valve surgeries will include in the study.
Exclusion criteria
Exclusion criteria: -emergency surgery, -an allergy to local anaesthetics, -hemodynamic instability (left ventricular ejection fraction & EF 30%) -congestive heart failure, hepatic or renal failure, -a history of drug abuse or chronic pain, -psychiatric problems, -secondary surgery, - inability to provide inform
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess whether the combination of melatonin and B/L pectointercostal fascial block provides prolonged adequate analgesia and promotes rapid recovery.Timepoint: numeric rating scale (NRS) at 0, 3, 6-, 12-, 18-, and 24-hours during breathing of normal tidal volume and with cough. | — |
Secondary
| Measure | Time frame |
|---|---|
| The requirement of fentanyl during the postoperative period, extubation time, postoperative delirium and length of ICU, and hospital stay. To evaluate anxiety and sedation levels in the preoperative area before shifting to the 9 operation theatre.Timepoint: preoperative, postoperatively 24 hrs | — |
Countries
India
Contacts
Public ContactDrJitendra kalbande
aiims raipur
Outcome results
None listed