Comparing two types methods of giving dexmedetomidine drug for seeing effects on increased pain control and muscle relaxation

COMPARISON OF THE EFFECT OF INTRAVENOUS DEXMEDETOMIDINE ADMINISTERED AS BOLUS OR BOLUS PLUS INFUSION ON SENSORY AND MOTOR BLOCKADE AFTER SPINAL ANAESTHESIA IN LOWER LIMB SURGERIES- A PROSPECTIVE CONTROL STUDY - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/05/067691

Enrollment

222

Registered

2024-05-20

Start date

Unknown

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine bolus vs bolus plus infusion: Dexmedetomidine calculated according to body weight and group alloted into. In bolus group 1 mcg/kg for 10 minutes in beginning of surgery,

Eligibility

Inclusion criteria

Inclusion criteria: Lower limb orthopedic surgery done under spinal anesthesia

Exclusion criteria

Exclusion criteria: Asa 3 Cardiac disease Bradycardia Hemodynamic unstable Allergy to dexmedetomidine or local anesthesia

Design outcomes

Primary

Measure	Time frame
To check for Improved and prolonged sensory and motor blockadeTimepoint: Intraoperative and end of surgery and 2 hours iin PACU.	—

Secondary

Measure	Time frame
Prevention of intraoperative & postoperative shiveringTimepoint: 30 mins postspinal,end of surgery & 1hour after surgery	—

Countries

India

Contacts

Public ContactDrsai sanjana

Sri ramachandra medical college and hospital and research Centre

vjram2001@yahoo.co.in9841219820

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026